Na+ channel dia 300m^-2 in squid axon 

Ca+ current is slower than Na+ current 



Resting potentials(sp pump) then depolarized(enter Na to cell) then Action potential then Neurotransmitter then Communication

 Action Potential(AP) Alteration tend to heart desease, cardiac arithmia, death 

AP of heart recorded to produce ECG 

An action potential is sequence of changes in the voltage across a membrane

Food: Black Cumin(+), mouri, betel leaf(++) 

When Na, Cl, Ca enter then K leave cell for better heart contraction 

3 ion Na enter to cell then 1 ion Ca leave the cell 

2 ion K enter the cell then 3 Na out

ion  Na In then 1 ion H out

Most of passive current carried by K+

Greater the Na gradient the more glucose enter to the cell 

If Na out of cell is low the glucose transport stop

Na Glucose symporter lay on SP pump 

50 million sp pump in each cell of kidney

Increasing Volt cause more Na chennel open

High Ca can damage mitocondria and increase oxidative stress

Na flow into rod outer segment 

Na chennel of eye is open but close due to increase Ca 

First vitamin reduce glucose if vitamin is low 

then Na reduce glucose if Na is low

then insulin reduce the glucose 

When vitamin is low to low the glucose then insuline secrete Nacl

receptor in mouth for test 

The Na chennel called Enac that blocked by drug 

Na for kidney to filter waste product 

In dark Ca chennel is hi,

glutamate release hi in light Ca chennel is reduce, glutamate release is reduce 

Na enter to cell is hi in dark than light 

ECF: NaCl,Ca, Glucose,Hco3

Icf: K,mg,po,Protien Increase Ca active the Na Ca Exchanger Increase Na active SP pump Increase Cause cell death 

K channel open to close Ca channel Dichlofenac sodium for Ca pump out from cell to contract mscle In early dev of organ AP Carried by Ca current than Na current

Boron:

For proper absorbtion of Ca


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