Addison ’ s disease is usually associated with hypotension due to excess renal sodium loss, which results in hyponatraemia and intravascular volume depletion.
Addison’s Disease: Addison’s disease results when the adrenal glands are damaged, which hampers the body’s ability to produce aldosterone. This means that Addison’s disease patients cannot reabsorb sufficient amounts of sodium, and they experience dangerously-low sodium levels. Thus, patients with Addison’s disease often experience very strong salt cravings.
Addison’s disease is a rare chronic condition in which your adrenal glands don’t produce enough of the hormones cortisol and aldosterone. It's most often caused by an autoimmune attack. It's treatable with medication
Cortisol is a hormone that helps your body respond to stress, including the stress of illness, injury or surgery. It also helps maintain your blood pressure, heart function, immune system and blood glucose (sugar) levels. Cortisol is essential for life.
People who have the following autoimmune disease are also at higher risk of developing the autoimmune (most common) form of Addison's disease:
- Type I diabetes.(hi glucose)
- Pernicious anemia.(B12 deficiency, intrinsic factor,diminished dietary B12 absorption due to IF deficiency)
- Graves' disease.(hyperthyroidism)
- Chronic thyroiditis.(Hashimoto, hyporthyroidism)
- Dermatitis herpetiformis.(itchy skin)
- Vitiligo.(loss of skin color)
- Myasthenia gravis.(destroy the communication between nerves and muscle)
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