Ringer's lactate solution

From Wikipedia, the free encyclopedia
Ringer's lactate solution
A bottle of Ringer's lactate solution
Clinical data
Other namescompound sodium lactate, sodium lactate solution, Hartmann's solution, Ringer-Locke's solution, Ringer-lactate, lactated Ringer's solution (LRS)
AHFS/Drugs.comFDA Professional Drug Information
License data
Routes of
administration
intravenous, topical, subcutaneous
ATC code

Ringer's lactate solution (RL), also known as sodium lactate solution, Lactated Ringer’s, and Hartmann's solution, is a mixture of sodium chloridesodium lactatepotassium chloride, and calcium chloride in water.[1] It is used for replacing fluids and electrolytes in those who have low blood volume or low blood pressure.[2] It may also be used to treat metabolic acidosis and to wash the eye following a chemical burn.[2][3] It is given by intravenous infusion or applied to the affected area.[2][3]

Side effects may include allergic reactionshigh blood potassiumhypervolemia, and high blood calcium.[2] It may not be suitable for mixing with certain medications and some recommend against use in the same infusion as a blood transfusion.[4] Ringer's lactate solution has a lower rate of acidosis as compared with normal saline.[1][4] Use is generally safe in pregnancy and breastfeeding.[2] Ringer's lactate solution is in the crystalloid family of medications.[5] It is isotonic, i.e. it has the same tonicity as blood.[2]

Ringer's solution was invented in the 1880s; lactate was added in the 1930s.[4] It is on the World Health Organization's List of Essential Medicines.[6] Lactated Ringer's is available as a generic medication.[1] For people with liver dysfunction, Ringer's acetate may be a better alternative with the lactate replaced by acetate.[7] In Scandinavia Ringer's acetate is typically used.[8]

Post a Comment

أحدث أقدم