Ringer's lactate solution
 A bottle of Ringer's lactate solution | |
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| Other names | compound sodium lactate, sodium lactate solution, Hartmann's solution, Ringer-Locke's solution, Ringer-lactate, lactated Ringer's solution (LRS) |
| AHFS/Drugs.com | FDA Professional Drug Information |
| License data | |
| Routes of administration | intravenous, topical, subcutaneous |
| ATC code | |
Ringer's lactate solution (RL), also known as sodium lactate solution, Lactated Ringer’s, and Hartmann's solution, is a mixture of sodium chloride, sodium lactate, potassium chloride, and calcium chloride in water.[1] It is used for replacing fluids and electrolytes in those who have low blood volume or low blood pressure.[2] It may also be used to treat metabolic acidosis and to wash the eye following a chemical burn.[2][3] It is given by intravenous infusion or applied to the affected area.[2][3]
Side effects may include allergic reactions, high blood potassium, hypervolemia, and high blood calcium.[2] It may not be suitable for mixing with certain medications and some recommend against use in the same infusion as a blood transfusion.[4] Ringer's lactate solution has a lower rate of acidosis as compared with normal saline.[1][4] Use is generally safe in pregnancy and breastfeeding.[2] Ringer's lactate solution is in the crystalloid family of medications.[5] It is isotonic, i.e. it has the same tonicity as blood.[2]
Ringer's solution was invented in the 1880s; lactate was added in the 1930s.[4] It is on the World Health Organization's List of Essential Medicines.[6] Lactated Ringer's is available as a generic medication.[1] For people with liver dysfunction, Ringer's acetate may be a better alternative with the lactate replaced by acetate.[7] In Scandinavia Ringer's acetate is typically used.[8]
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